Veklury® (remdesivir)
Use of COVID-19 Vaccines
Gilead Sciences, Inc. is providing this document to you, a US Healthcare Professional, in response to your unsolicited request for medical information.
Gilead Sciences, Inc. is providing this document to you, a US Healthcare Professional, in response to your unsolicited request for medical information.
Veklury® (remdesivir)
Use of COVID-19 Vaccines
Some data may be outside of the US FDA-approved Prescribing Information. In providing this data, Gilead Sciences, Inc. is not making any representation as to its clinical relevance or to the use of any Gilead product(s). For information about the approved conditions of use of any Gilead drug product, please consult the FDA approved prescribing information.
The full indication, important safety information, and boxed warnings are available at:
www.gilead.com/-/media/files/pdfs/medicines/covid-19/veklury/veklury_pi.
Product Labeling
Subjects in RDV clinical trials NIAID ACTT-1, GS-US-540-5773 (SIMPLE severe), GS-US-540-5774 (SIMPLE moderate), GS-US-540-9012 (PINETREE), and GS-US-540-5823 (CARAVAN) were unvaccinated for COVID-19.1
Study GS-US-540-5912 evaluated RDV 200 mg once daily for 1 day followed by RDV 100 mg once daily for 4 days (for a total of up to 5 days of intravenously administered therapy) in 243 hospitalized adult subjects with confirmed COVID-19 and renal impairment. 31 subjects (13%) had received a COVID-19 vaccine.1 Outcomes by vaccination status have not been published.
Available Data
Currently, there are no data available on RDV and the use of COVID-19 vaccines.
Please refer to the manufacturer of the appropriate COVID-19 vaccine for additional information.
Literature Search
A literature search was conducted in Ovid MEDLINE and Embase databases for studies published between 1946 and March 14, 2025 using search terms that included Veklury, remdesivir, GS-5734, GS-441524, COVID-19 vaccine and related search terms. No relevant citations were found.
References
1. Enclosed. Gilead Sciences Inc. Veklury® (remdesivir) for injection, for intravenous use. VEKLURY® (remdesivir) injection, for intravenous use. U.S. Prescribing Information. Foster City, CA.
Abbreviations
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ACTT=Adaptive
COVID-19 Treatment
Trial
CARAVAN=Clinical Administration of RDV
After COVID-19
Diagnosis in Children
COVID-19=coronavirus
disease 2019 RDV=remdesivir
Product Label
For the full indication, important safety information, and boxed warning(s), please refer to the Veklury US Prescribing Information available at:
www.gilead.com/-/media/files/pdfs/medicines/covid-19/veklury/veklury_pi.
Follow Up
For any additional questions, please contact Gilead Medical Information at:
☎1‐866‐MEDI‐GSI (1‐866‐633‐4474) or www.askgileadmedical.com
Adverse Event Reporting
Please report all adverse events to:
Gilead Global Patient Safety ☎ 1-800-445-3235, option 3 or
www.gilead.com/utility/contact/report-an-adverse-event
FDA MedWatch Program by ☎ 1-800-FDA-1088 or MedWatch, FDA, 5600 Fishers Ln, Rockville, MD 20852 or www.accessdata.fda.gov/scripts/medwatch
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VEKLURY, GILEAD, and the GILEAD logo are registered trademarks of Gilead Sciences, Inc., or its related companies.
© 2025 Gilead Sciences, Inc.
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